The psychometric properties of the Leicester Cough Questionnaire and Respiratory Symptoms in CF tool in cystic fibrosis: A preliminary study

AuthorsWard, N.
Stiller, K.
Rowe, H.
Holland, AE.
TypeJournal Article (Original Research)
JournalJournal of Cystic Fibrosis
PubMed ID27986494
Year of Publication2017
URLhttp://www.sciencedirect.com/science/article/pii/S1569199316306695
DOIhttp://dx.doi.org/10.1016/j.jcf.2016.11.011
AbstractBACKGROUND:
There are few tools to quantify the impact of cough in cystic fibrosis (CF). The psychometric properties of the Leicester Cough Questionnaire (LCQ) and Respiratory Symptoms in CF (ReS-CF) tool were investigated in adults with CF.
METHODS:
Validity and reliability were assessed in clinically stable participants who completed the questionnaires twice, along with the Cystic Fibrosis Questionnaire - Revised (CFQ-R). Responsiveness was assessed by change in questionnaires following treatment for an acute respiratory exacerbation.
RESULTS:
Correlations between the LCQ and CFQ-R respiratory domain were moderate (n=59, rs=0.78, p<0.001). Correlations between ReS-CF and CFQ-R respiratory domain were fair (rs=-0.50, p<0.001). The LCQ total score was repeatable (ICC 0.92, 95%CI 0.87-0.96, n=50). In those reporting improvement in symptoms following treatment (n=36), LCQ total score had a mean change of 4.6 (SD 3.7) and effect size of 1.2.
CONCLUSIONS:
The LCQ and ReS-CF appear to be valid, reliable and responsive in CF.
TRIAL REGISTRATION:
www.anzctr.org.au: ACTRN12615000262505.

http://www.ibas.org.au/what-we-do/publications/3872888


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