Longer versus a shorter duration exercise rehabilitation program following lung transplant: A randomised controlled trial.

AuthorsFuller, LM.
Button, B.
Tarrant, B.
Steward, R.
Snell, G.
Holland, AE.
TypeJournal Article (Original Research)
JournalArchives of physical medicine and rehabilitation
Year of Publication2016
URLhttps://www.sciencedirect.com/science/article/pii/S0003999316310991
DOIhttp://dx.doi.org/10.1016/j.apmr.2016.09.113
Download 1-s20-S0003999316310991_.pdf (533.0 KB)
AbstractObjective
To investigate the effects of a supervised longer- (14wk) versus shorter-duration (7wk) rehabilitation program after lung transplantation (LTX).
Design
Randomized controlled trial.
Setting
Outpatient rehabilitation gym setting.
Participants
Post-LTX patients aged ≥18 years (N=66; 33 women; mean age, 51±13y) who had undergone either single LTX or bilateral LTX.
Intervention
Outpatient rehabilitation program consisting of thrice-weekly sessions with cardiovascular training on bike ergometer and treadmill plus upper and lower limb strength training.
Main Outcome Measures
Measures were taken at baseline, 7 weeks, 14 weeks, and 6 months by assessors who were blinded to group allocation. Functional exercise capacity was measured by the 6-minute walk test (6MWT). Strength of quadriceps and hamstrings was measured on an isokinetic dynamometer and recorded as average peak torque of 6 repetitions for both muscles. Quality of life (QOL) was assessed with the Medical Outcomes Study 36-Item Short-Form Health Survey.
Results
Of the participants, 86% had bilateral LTX and 41% had primary diagnosis of chronic obstructive pulmonary disease. The 6MWT increased in both groups with no significant difference between groups at any time point (mean 6mo 6MWD: short, 590±85m vs long, 568±127m; P =0.5). Similarly, at 6 months, there was no difference between groups in quadriceps average peak torque (mean, 115±38Nm vs 114±40Nm, respectively; P =.59), hamstring average peak torque (57±18Nm vs 52±19Nm, respectively; P =.36), or mental or physical health domains of quality of life.
Conclusions
Shorter duration (7wk) of rehabilitation achieves comparable outcomes with 14 weeks of supervised rehabilitation for functional exercise capacity, lower limb strength, and quality of life at 6 months after LTX.

http://www.ibas.org.au/what-we-do/publications/3872870


< More publications



Notch monitoring in sleepNOTCH MONITORING IN SLEEP

Sleep apnea is a condition where breathing is abnormal during sleep. There are two main forms of sleep apnea: obstructive and central. For obstructive sleep apnea, breathing is reduced because the airway...

Respiratory Biomarkers in Motor Neurone DiseaseRESPIRATORY BIOMARKERS IN MOTOR NEURONE DISEASE

The inability to breathe is unfortunately the most common cause of death in people living with Motor Neurone Disease (MND). Last year, our clinical research group in Melbourne reported that breathing...

ResearchFest 2026RESEARCHFEST 2026

ResearchFest 2026 at Austin Health launched new research flagships and honored Professor Mark Howard (Distinguished Scientist) and Professor Eliza Hawkes (Women in Research Award), with insights from Peter Doherty.

Championing Sleep Research!CHAMPIONING SLEEP RESEARCH!

We are announcing exciting updates to our Early and Mid-Career Researcher (EMCR) representation at the Institute for Breathing and Sleep (IBAS). The MSRC extend a warm thank you to Charissa Zaga and welcome Jessica Manousakis!

ANZSRS Life Membership for Danny BrazzaleANZSRS LIFE MEMBERSHIP FOR DANNY BRAZZALE

Danny Brazzale has earned a prestigious ANZSRS Life Membership—held by only 11 people—for his global leadership and dedicated mentorship in respiratory science.

Perth Highlights: TSANZSRS 2026PERTH HIGHLIGHTS: TSANZSRS 2026

A huge congratulations to all our team members who participated in the excellent workshops and meetings at the TSANZSRS Annual Scientific Meeting in Perth in March 2026! Well Done!

Institute for Breathing and Sleep

Level 5, Harold Stokes Building, Austin Health
145 Studley Road
Heidelberg, Victoria, 3084

(03) 9496 5390

Email Us

Donate