OSA, CPAP and Depression (COSAD)

Obstructive Sleep Apnoea (OSA) is a highly prevalent, chronic illness, characterised by
repetitive collapse of the airway during sleep producing oxygen desaturations and sleep
disruption. OSA is associated with cognitive deficits, reduced quality of life, and depressed
mood. The prevalence of both depressive symptoms and major depressive disorder (MDD) are significantly higher in OSA patients compared to the general community. Both conditions pose a significant health risk and significantly impact on brain function and general well-being. Currently there is little clinical evidence to support whether treatment of OSA improves depressive symptoms in OSA patients with comorbid depressive symptoms or MDD.

The aim of this study is to determine whether CPAP treatment improves depressive symptoms and cognitive functioning over the short and long term. This study will provide much-needed clinical evidence of the efficacy of CPAP therapy for improving both depression and cognitive functioning in OSA.


Full Name

Do Treatment Interventions for Obstructive Sleep Apnoea Reduce Depressive Symptoms in Patients with Comorbid Depression?

Primary Investigator

Melinda Jackson

Stream

Sleep > Obstructive Sleep Apnoea

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